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Translational application of neuroimaging in major depressive disorder: a review of psychoradiological

Ziqi Chen, Xiaoqi Huang, Qiyong Gong, Bharat B. Biswal

Frontiers of Medicine 2021, Volume 15, Issue 4,   Pages 528-540 doi: 10.1007/s11684-020-0798-1

Abstract: Major depressive disorder (MDD) causes great decrements in health and quality of life with incrementsforeseeable clinical applications for different MRI modalities were introduced according to their role in disorder

Keywords： psychoradiology     major depressive disorder     MRI     biomarker    

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Cannabidiol prevents depressive-like behaviors through the modulation of neural stem cell differentiation

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 227-239 doi: 10.1007/s11684-021-0896-8

Abstract: The administration of CBD rescued depressive-like symptoms in CRS mice and prevented rNSCs overactivation

Keywords： cannabidiol     depression     radial neural stem cells     neurogenesis    

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Relationship between expression of hepatocyte grow factor and apoptosis of trophoblasts in hypertensive disorder

OUYANG Shan, ZHANG Qinghua, QIAO Fuyuan

Frontiers of Medicine 2007, Volume 1, Issue 4,   Pages 386-389 doi: 10.1007/s11684-007-0075-6

Abstract: growth factor (HGF) and Fas in placentas of uncomplicated pregnant women and those with hypertensive disorder

Keywords： pregnancy     concentration     possible relationship     responsible     hepatocyte    

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The Major Root Causes of Smog in China and Technologies and Solutions to Reduce It

Ke Liu

Frontiers of Engineering Management 2016, Volume 3, Issue 4,   Pages 343-348 doi: 10.15302/J-FEM-2016053

Abstract: This paper discusses the two major root causes of smog in China.The second major cause of smog is the low quality diesel and outdated diesel engines used in China.

Keywords： smog     emissions     coal refining     coal utilization     solutions    

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Arbuscular mycorrhizal associations and the major regulators

Li XUE, Ertao WANG

Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 3,   Pages 296-306 doi: 10.15302/J-FASE-2020347

Abstract:

Plants growing in natural soils encounter diverse biotic and abiotic stresses and have adapted with sophisticated strategies to deal with complex environments such as changing root system structure, evoking biochemical responses and recruiting microbial partners. Under selection pressure, plants and their associated microorganisms assemble into a functional entity known as a holobiont. The commonest cooperative interaction is between plant roots and arbuscular mycorrhizal (AM) fungi. About 80% of terrestrial plants can form AM symbiosis with the ancient phylum Glomeromycota. A very large network of extraradical and intraradical mycelium of AM fungi connects the underground biota and the nearby carbon and nutrient fluxes. Here, we discuss recent progress on the regulators of AM associations with plants, AM fungi and their surrounding environments, and explore further mechanistic insights.

Keywords： AM symbiosis     signal     regulators     nutrients     phosphate     microbiota    

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The development and benefits of metformin in various diseases

Frontiers of Medicine 2023, Volume 17, Issue 3,   Pages 388-431 doi: 10.1007/s11684-023-0998-6

Abstract: Metformin has been used for the treatment of type II diabetes mellitus for decades due to its safety, low cost, and outstanding hypoglycemic effect clinically. The mechanisms underlying these benefits are complex and still not fully understood. Inhibition of mitochondrial respiratory-chain complex I is the most described downstream mechanism of metformin, leading to reduced ATP production and activation of AMP-activated protein kinase (AMPK). Meanwhile, many novel targets of metformin have been gradually discovered. In recent years, multiple pre-clinical and clinical studies are committed to extend the indications of metformin in addition to diabetes. Herein, we summarized the benefits of metformin in four types of diseases, including metabolic associated diseases, cancer, aging and age-related diseases, neurological disorders. We comprehensively discussed the pharmacokinetic properties and the mechanisms of action, treatment strategies, the clinical application, the potential risk of metformin in various diseases. This review provides a brief summary of the benefits and concerns of metformin, aiming to interest scientists to consider and explore the common and specific mechanisms and guiding for the further research. Although there have been countless studies of metformin, longitudinal research in each field is still much warranted.

Keywords： metformin     metabolism     cancer     aging     neurological disorder    

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Life cycle and performance based seismic design of major bridges in China

FAN Lichu

Frontiers of Structural and Civil Engineering 2007, Volume 1, Issue 3,   Pages 261-266 doi: 10.1007/s11709-007-0033-z

Abstract: The idea of life cycle and performance based seismic design of major bridges is introduced.components, different seismic design levels and expected performance objectives are suggested for the majorassessment, are also proposed to be the important issues to study in order to guide the seismic design of major

Keywords： controllability     progressive     reparability     different     important    

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Progress on major genes for high fecundity in ewes

Qiuyue LIU,Zhangyuan PAN,Xiangyu WANG,Wenping HU,Ran DI,Yaxing YAO,Mingxing CHU

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 4,   Pages 282-290 doi: 10.15302/J-FASE-2014042

Abstract: The existence of major genes affecting fecundity in sheep flocks throughout the world has been demonstratedThree major genes whose mutations can increase ovulation rate have been discovered, and all related toIn addition, several putative major genes need to be verified.This review is focused on the identification of the mutations and mechanisms whereby the major genes

Keywords： major gene     ovulation rate     sheep     reproduction    

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Value Management Practices on Major Construction Projects and Green Building

Ru-jiang Zhao,Wung Hee Moh

Frontiers of Engineering Management 2016, Volume 3, Issue 2,   Pages 147-157 doi: 10.15302/J-FEM-2016018

Abstract: The paper starts with background information on value management (VM) in the construction industry and current development situation of the green building industry, and costs and profitability of green buildings. The paper continues with detailed analyses of the findings, covering new developments and perceptions of VM, and applications of VM in the industry. The paper also reports case studies on the practices adopted in the planning and design management phase of SIPO Guangdong Patent Examination Cooperation Center and in the construction management phase of Guangzhou International Bio-Island Standard Property Unit II project. As revealed by the practices, the value-adds and savings in construction costs through the application of VM are important for the developers, and the contributions of VM application in green building projects are significant to achieving the expected targets and to resolving the design and construction challenges encountered in the development of green building industry. And the paper presents, findings on how VM can improve construction management and coordination of several ongoing construction projects and on how VM can be systematically implemented by phases, and discussions on other potential benefits of using VM systems.

Keywords： value management (VM)     VM theory and practices     Chinese construction industry     green buildings    

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Temporal trend of mortality from major cancers in Xuanwei, China

Hualiang Lin,Bofu Ning,Jihua Li,Guangqiang Zhao,Yunchao Huang,Linwei Tian

Frontiers of Medicine 2015, Volume 9, Issue 4,   Pages 487-495 doi: 10.1007/s11684-015-0413-z

Abstract: This study aimed to investigate the temporal trend of eight major cancers in Xuanwei County using datastudies are warranted to systematically examine the underlying reasons for the temporal trend of the major

Keywords： cancer     mortality     Xuanwei     temporal trend    

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Environmental and human health impact assessment of major interior wall decorative materials

Bingqing ZHANG, Ruochen ZENG, Xiaodong LI

Frontiers of Engineering Management 2019, Volume 6, Issue 3,   Pages 406-415 doi: 10.1007/s42524-019-0025-4

Abstract: Despite the growing interest in green products in the interior wall decorative material market, knowledge gaps exist because determining which product is more environmental and user friendly than the others is difficult. This work assesses the environmental and human health profiles of interior latex and wallpaper. Two interior latex products of different raw material ratios and one non-woven wallpaper product are considered. The environmental impact assessment follows life cycle assessment (LCA) methodology and applies Building Environmental Performance Analysis System (BEPAS). The human health impact is based on impact-pathway chain and is performed using Building Health Impact Analysis System (BHIAS). The assessment scope, associated emissions, and territorial scope of various emissions are defined to facilitate comparison study of interior wall decorative products. The impacts are classified into 15 categories belonging to three safeguard areas: ecological environment, natural resources, and human health. The impacts of categories are calculated and monetized using willingness to pay (WTP) and disability-adjusted life year (DALY) and summarized as an integrated external cost of environmental and human health impacts. Assessment results reveal that the integrated impact of interior latex is lower than that of non-woven wallpaper, and the interior latex of low quality causes low life cycle integrated impact. The most impacted categories are global warming, respiratory effects, and water consumption. Hotspots of product manufacturing are recognized to promote green product design.

Keywords： life cycle assessment     human health impact     integrated assessment     interior wall decorative material     green product    

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Review on Major Planning Projects & Frontier Issues about Global Engineering Science and Technology inMajor Countries

Song Chao,Sun Shengkai,Chen Jindong,Wang Yaqiong,Kan Xiaowei,Wei Chang and Cui Jian

Strategic Study of CAE 2017, Volume 19, Issue 1,   Pages 4-12 doi: 10.15302/J-SSCAE-2017.01.002

Abstract:

This paper examines recent major strategic planning projects in engineeringscience and technology from several major countries around the world, and briefly analyzes the currentdevelopment status of major fields.

Keywords： engineering science and technology     major countries     major planning projects     frontier issue     focus    

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Implementation of a flexible Major Vacation Toll-free Program for small passenger vehicles in China

Meng XU, Ziyou GAO

Frontiers of Engineering Management 2017, Volume 4, Issue 4,   Pages 498-499 doi: 10.15302/J-FEM-2017111

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Risk factors for ventilator-associated pneumonia among patients undergoing major oncological surgery

Yutao Liu, Yaxia Di, Shuai Fu

Frontiers of Medicine 2017, Volume 11, Issue 2,   Pages 239-246 doi: 10.1007/s11684-017-0509-8

Abstract:

Patients undergoing major oncological surgery for head and neck cancer (SHNC) have a particularlyEnterobacteriaceae (32.1%), Pseudomonas(20.8%), and Haemophilus (16.9%) were the major

Keywords： ventilator-associated pneumonia (VAP)     pneumonia     risk factors     surgery for head and neck cancer (SHNC)    

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CRITICAL PROCESSES AND MAJOR FACTORS THAT DRIVE NITROGEN TRANSPORT FROM FARMLAND TO SURFACE WATER BODIES

Frontiers of Agricultural Science and Engineering 2023, Volume 10, Issue 4,   Pages 541-552 doi: 10.15302/J-FASE-2023518

Abstract: The present study systematically reviewed the critical processes and major factors that nitrogen transport

Keywords： nitrogen     loss from soil     transformation     farm field scale     watershed scale    

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Title Author Date Type Operation

Translational application of neuroimaging in major depressive disorder: a review of psychoradiological

Ziqi Chen, Xiaoqi Huang, Qiyong Gong, Bharat B. Biswal

Journal Article

Cannabidiol prevents depressive-like behaviors through the modulation of neural stem cell differentiation

Journal Article

Relationship between expression of hepatocyte grow factor and apoptosis of trophoblasts in hypertensive disorder

OUYANG Shan, ZHANG Qinghua, QIAO Fuyuan

Journal Article

The Major Root Causes of Smog in China and Technologies and Solutions to Reduce It

Ke Liu

Journal Article

Arbuscular mycorrhizal associations and the major regulators

Li XUE, Ertao WANG

Journal Article

The development and benefits of metformin in various diseases

Journal Article

Life cycle and performance based seismic design of major bridges in China

FAN Lichu

Journal Article

Progress on major genes for high fecundity in ewes

Qiuyue LIU,Zhangyuan PAN,Xiangyu WANG,Wenping HU,Ran DI,Yaxing YAO,Mingxing CHU

Journal Article

Value Management Practices on Major Construction Projects and Green Building

Ru-jiang Zhao,Wung Hee Moh

Journal Article

Temporal trend of mortality from major cancers in Xuanwei, China

Hualiang Lin,Bofu Ning,Jihua Li,Guangqiang Zhao,Yunchao Huang,Linwei Tian

Journal Article

Environmental and human health impact assessment of major interior wall decorative materials

Bingqing ZHANG, Ruochen ZENG, Xiaodong LI

Journal Article

Review on Major Planning Projects & Frontier Issues about Global Engineering Science and Technology inMajor Countries

Song Chao,Sun Shengkai,Chen Jindong,Wang Yaqiong,Kan Xiaowei,Wei Chang and Cui Jian

Journal Article

Implementation of a flexible Major Vacation Toll-free Program for small passenger vehicles in China

Meng XU, Ziyou GAO

Journal Article

Risk factors for ventilator-associated pneumonia among patients undergoing major oncological surgery

Yutao Liu, Yaxia Di, Shuai Fu

Journal Article

CRITICAL PROCESSES AND MAJOR FACTORS THAT DRIVE NITROGEN TRANSPORT FROM FARMLAND TO SURFACE WATER BODIES

Journal Article